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Sensitivity boost for biomolecular NMR

As the market leader, Bruker introduces the world’s first commercially available solid-state dynamic nuclear polarization-enhanced NMR system (DNP-NMR)

Bruker’s 263, 395 and 527 GHz DNP-NMR Spectrometers are the world’s first commercially available solid-state DNP-NMR systems. All spectrometers enable extended DNP solid-state biomolecular NMR experiments delivering unsurpassed sensitivity for exciting new applications. 


Signal enhancements from 20 to a factor of 80 on multiple samples are possible and system optimization is ongoing for even higher DNP efficiency. The new high power gyrotron system, delivering microwaves at 263 GHz and 395 GHz, are robust, safe and easy-to-use, enabling long term DNP experiments without time limitations.  

Experiments performed at a low temperature of ~100 K benefit from the innovative low-temperature MAS probe that enables sample polarization in-situ, directly at the NMR field.


  • Turn-key solution for DNP-enhanced solids NMR experiments at high field
  • Polarization enhancement yields factor up to 80 gain in sensitivity for solid-state NMR
  • Unique high power microwave sources
  • Easy-to-use software-controlled high power gyrotron
  • Optimum beam propagation to the sample ensured by microwave transmission lines
  • New low-temperature MAS probe technology with built-in waveguide and cold spinning gas supply
  • AVANCE™ III HD 400, 600 and 800 wide bore NMR system