AVANCE NEO KONSOLLAR

The AVANCE NEO consoles for NMR feature even faster control, improved dynamic range and greater flexibility and scalability than ever before.

Performance

The AVANCE NEO console offers faster control and improved dynamic range for greater flexibility and scalability

Automation

Several options exist for the wide range of NMR instruments to reduce hands-on time and increase throughput.

Transceive

Each NMR channel has both transmit and receive capabilities meaning each channel is its own independent spectrometer with the full RF generation, transmission and receive infrastructure.

Features

While its predecessor, the AVANCE III HD, already provided cutting-edge NMR performance, the AVANCE NEO takes this a step further. It features even faster control, improved dynamic range and greater flexibility and scalability.

The AVANCE NEO is based on a ‘transceive’ principle, meaning each NMR channel has both transmit and receive capabilities. This architecture provides the greatest flexibility in terms of instrument configuration and multi-channel operation. Multi-receive experiments are easily implemented with this new approach.

Also new in the AVANCE NEO is the concept of an embedded acquisition server and an associated client-server software architecture (TopSpin 4 and higher). This leaves the spectrometer independent of the client computer, thus giving the user the opportunity to control the system via an operating system and location of choice, like the cloud.

With the frequency range now extended from 200 MHz to 1.2 GHz, and with various functional enhancements in setup and diagnostics, the AVANCE NEO is well positioned to serve as the research platform of choice for the current and the next generation of NMR spectroscopists.

Validating Hits Through NMR as an Orthogonal Biophysical Method	Nutritious Krill Oil Obtained by Novel Environmentally-Friendly Extraction	New Horizons for NMR in the Biopharmaceutical Industry
For the first time, a research team led by Michael Hennig presented a SPR-based fragment screen of a peptide-binding G protein-coupled receptor, in combination with NMR, to identify, validate and subsequently characterize hit molecules. They used SPR as a primary method to screen.	A novel methodology for the extraction of krill oil has recently been described using the solvents ethanol and hexane, which are environmentally friendly. The krill oil obtained using the new extraction process was compared with that obtained using the traditional subcritical extraction method. Phospholipids, fatty acid and antioxidant content of the krill oil resulting from each extraction method were analysed by NMR using a Bruker AVANCE Spectrometer 500.	A recent study by Luke Arbogast and colleagues showed how advances in NMR spectroscopy are beginning to lead to solutions to this challenge.